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Faulty oxygen sensing disrupts angiomotin function in trophoblast cell migration and predisposes to preeclampsia
Human placenta development and a successful pregnancy is incumbent upon precise oxygen-dependent control of trophoblast migration/invasion. Persistent low oxygen leading to failed trophoblast invasion promotes inadequate spiral artery remodeling, a characteristic of preeclampsia. Angiomotin (AMOT) i...
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| Foilsithe in: | JCI Insight |
|---|---|
| Main Authors: | , , , , , , |
| Formáid: | Artigo |
| Teanga: | Inglês |
| Foilsithe: |
American Society for Clinical Investigation
2019
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| Ábhair: | |
| Rochtain Ar Líne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6538363/ https://ncbi.nlm.nih.gov/pubmed/30996134 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.127009 |
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