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Vaccine-induced ICOS(+)CD38(+) circulating Tfh are sensitive biosensors of age-related changes in inflammatory pathways

Humoral immune responses are dysregulated with aging, but the cellular and molecular pathways involved remain incompletely understood. In particular, little is known about the effects of aging on T follicular helper (Tfh) CD4 cells, the key cells that provide help to B cells for effective humoral im...

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Detalhes bibliográficos
Publicado no:Cell Rep Med
Main Authors: Herati, Ramin Sedaghat, Silva, Luisa Victoria, Vella, Laura A., Muselman, Alexander, Alanio, Cecile, Bengsch, Bertram, Kurupati, Raj K., Kannan, Senthil, Manne, Sasikanth, Kossenkov, Andrew V., Canaday, David H., Doyle, Susan A., Ertl, Hildegund C.J., Schmader, Kenneth E., Wherry, E. John
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8149371/
https://ncbi.nlm.nih.gov/pubmed/34095875
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.xcrm.2021.100262
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