Circulating CXCR5(+)PD-1(+) response predicts influenza vaccine antibody responses in young adults but not elderly adults

Although influenza vaccination is recommended for all adults annually, the incidence of vaccine failure, defined as weak or absent increase in neutralizing antibody titers, is increased in the elderly compared to young adults. The T follicular helper subset of CD4 T cells (Tfh) provides B cell help...

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Autors principals: Herati, Ramin Sedaghat, Reuter, Morgan A., Dolfi, Douglas V., Mansfield, Kathleen D., Aung, Htin, Badwan, Osama Z., Kurupati, Raj K., Kannan, Senthil, Ertl, Hildegund, Schmader, Kenneth E., Betts, Michael R., Canaday, David H., Wherry, E. John
Format: Artigo
Idioma:Inglês
Publicat: 2014
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4170011/
https://ncbi.nlm.nih.gov/pubmed/25172499
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1302503
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