Vaccine-induced ICOS(+)CD38(+) circulating Tfh are sensitive biosensors of age-related changes in inflammatory pathways

Humoral immune responses are dysregulated with aging, but the cellular and molecular pathways involved remain incompletely understood. In particular, little is known about the effects of aging on T follicular helper (Tfh) CD4 cells, the key cells that provide help to B cells for effective humoral im...

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Bibliografiska uppgifter
I publikationen:Cell Rep Med
Huvudupphovsmän: Herati, Ramin Sedaghat, Silva, Luisa Victoria, Vella, Laura A., Muselman, Alexander, Alanio, Cecile, Bengsch, Bertram, Kurupati, Raj K., Kannan, Senthil, Manne, Sasikanth, Kossenkov, Andrew V., Canaday, David H., Doyle, Susan A., Ertl, Hildegund C.J., Schmader, Kenneth E., Wherry, E. John
Materialtyp: Artigo
Språk:Inglês
Publicerad: Elsevier 2021
Ämnen:
Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC8149371/
https://ncbi.nlm.nih.gov/pubmed/34095875
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.xcrm.2021.100262
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