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Avoiding Drug Resistance in HIV Reverse Transcriptase
HIV reverse transcriptase (RT) is an enzyme that plays a major role in the replication cycle of HIV and has been a key target of anti-HIV drug development efforts. Because of the high genetic diversity of the virus, mutations in RT can impart resistance to various RT inhibitors. As the prevalence of...
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| Veröffentlicht in: | Chem Rev |
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| Hauptverfasser: | , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2021
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8149104/ https://ncbi.nlm.nih.gov/pubmed/33507067 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.chemrev.0c00967 |
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