Partitioning and Spatial Distribution of Drugs in Ocular Surface Tissues

Ocular drug absorption after eye drop instillation has been widely studied, but partitioning phenomena and spatial drug distribution are poorly understood. We investigated partitioning of seven beta-blocking drugs in corneal epithelium, corneal stroma, including endothelium and conjunctiva, using is...

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Detalhes bibliográficos
Publicado no:Pharmaceutics
Main Authors: Balla, Anusha, Auriola, Seppo, Grey, Angus C., Demarais, Nicholas J., Valtari, Annika, Heikkinen, Emma M., Toropainen, Elisa, Urtti, Arto, Vellonen, Kati-Sisko, Ruponen, Marika
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8147976/
https://ncbi.nlm.nih.gov/pubmed/34064499
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics13050658
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