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Human corneal cell culture models for drug toxicity studies

In vivo toxicity and absorption studies of topical ocular drugs are problematic, because these studies involve invasive tissue sampling and toxic effects in animal models. Therefore, different human corneal models ranging from simple monolayer cultures to three-dimensional models have been developed...

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Detalhes bibliográficos
Publicado no:Drug Deliv Transl Res
Main Authors: Rönkkö, Seppo, Vellonen, Kati-Sisko, Järvinen, Kristiina, Toropainen, Elisa, Urtti, Arto
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5097077/
https://ncbi.nlm.nih.gov/pubmed/27613190
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13346-016-0330-y
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