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Human corneal cell culture models for drug toxicity studies

In vivo toxicity and absorption studies of topical ocular drugs are problematic, because these studies involve invasive tissue sampling and toxic effects in animal models. Therefore, different human corneal models ranging from simple monolayer cultures to three-dimensional models have been developed...

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Bibliografiska uppgifter
I publikationen:Drug Deliv Transl Res
Huvudupphovsmän: Rönkkö, Seppo, Vellonen, Kati-Sisko, Järvinen, Kristiina, Toropainen, Elisa, Urtti, Arto
Materialtyp: Artigo
Språk:Inglês
Publicerad: Springer US 2016
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5097077/
https://ncbi.nlm.nih.gov/pubmed/27613190
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13346-016-0330-y
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