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Human corneal cell culture models for drug toxicity studies

In vivo toxicity and absorption studies of topical ocular drugs are problematic, because these studies involve invasive tissue sampling and toxic effects in animal models. Therefore, different human corneal models ranging from simple monolayer cultures to three-dimensional models have been developed...

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Bibliografiske detaljer
Udgivet i:Drug Deliv Transl Res
Main Authors: Rönkkö, Seppo, Vellonen, Kati-Sisko, Järvinen, Kristiina, Toropainen, Elisa, Urtti, Arto
Format: Artigo
Sprog:Inglês
Udgivet: Springer US 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5097077/
https://ncbi.nlm.nih.gov/pubmed/27613190
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13346-016-0330-y
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