Partitioning and Spatial Distribution of Drugs in Ocular Surface Tissues

Ocular drug absorption after eye drop instillation has been widely studied, but partitioning phenomena and spatial drug distribution are poorly understood. We investigated partitioning of seven beta-blocking drugs in corneal epithelium, corneal stroma, including endothelium and conjunctiva, using is...

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Dettagli Bibliografici
Pubblicato in:Pharmaceutics
Autori principali: Balla, Anusha, Auriola, Seppo, Grey, Angus C., Demarais, Nicholas J., Valtari, Annika, Heikkinen, Emma M., Toropainen, Elisa, Urtti, Arto, Vellonen, Kati-Sisko, Ruponen, Marika
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2021
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8147976/
https://ncbi.nlm.nih.gov/pubmed/34064499
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics13050658
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