Nuclear PTEN enhances the maturation of a microRNA regulon to limit MyD88-dependent susceptibility to sepsis

Sepsis-induced organ damage is caused by systemic inflammatory response syndrome (SIRS), which results in substantial comorbidities. Therefore, it is of medical importance to identify molecular brakes that can be exploited to dampen inflammation and prevent SIRS development. The current study invest...

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書誌詳細
出版年:Sci Signal
主要な著者: Sisti, Flavia, Wang, Soujuan, Brandt, Stephanie L., Glosson-Byers, Nicole, Mayo, Lindsey, Son, Young min, Sturgeon, Sarah, Filgueiras, Luciano, Jancar, Sonia, Wong, Hector, Dela Cruz, Charles S., Andrews, Nathaniel, Alves-Filho, Jose Carlos, Cunha, Fernando Q., Serezani, C. Henrique
フォーマット: Artigo
言語:Inglês
出版事項: 2018
主題:
Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC8147521/
https://ncbi.nlm.nih.gov/pubmed/29717063
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.aai9085
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