Ectopic FOXP3 Expression in Combination with TGF-β1 and IL-2 Stimulation Generates Limited Suppressive Function in Human Primary Activated Thymocytes Ex Vivo

Regulatory T cells (Tregs), which are characterized by the expression of the transcription factor forkhead box P3 (FOXP3), are the main immune cells that induce tolerance and are regulators of immune homeostasis. Natural Treg cells (nTregs), described as CD4(+)CD25(+)FOXP3(+), are generated in the t...

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Detaylı Bibliyografya
Yayımlandı:Biomedicines
Asıl Yazarlar: Gallego-Valle, Jorge, Gil-Manso, Sergio, Pita, Ana, Bernaldo-de-Quirós, Esther, López-Esteban, Rocío, Martínez-Bonet, Marta, Pérez-Fernández, Verónica Astrid, Pérez-Caballero, Ramón, Pardo, Carlos, Gil-Jaurena, Juan-Miguel, Correa-Rocha, Rafael, Pion, Marjorie
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: MDPI 2021
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC8146103/
https://ncbi.nlm.nih.gov/pubmed/33922629
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biomedicines9050461
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