The Presence of a Marked Imbalance Between Regulatory T Cells and Effector T Cells Reveals That Tolerance Mechanisms Could Be Compromised in Heart Transplant Children

Regulatory T cells (Treg) are crucial for the induction and maintenance of graft tolerance. In pediatric heart transplant procedures, the thymus is routinely excised, removing the primary source of T-cell replenishment. Consequently, thymectomy joined to the effects of immunosuppression on the T-cel...

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Detalhes bibliográficos
Publicado no:Transplant Direct
Main Authors: Bernaldo-de-Quirós, Esther, López-Abente, Jacobo, Camino, Manuela, Gil, Nuria, Panadero, Esther, López-Esteban, Rocío, Martínez-Bonet, Marta, Pion, Marjorie, Correa-Rocha, Rafael
Formato: Artigo
Idioma:Inglês
Publicado em: Lippincott Williams & Wilkins 2021
Assuntos:
Pediatric Transplantation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8078462/
https://ncbi.nlm.nih.gov/pubmed/33928185
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/TXD.0000000000001152
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