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Proton Bridging in Catalysis by and Inhibition of Serine Proteases of the Blood Cascade System

Inquiries into the participation of short hydrogen bonds in stabilizing transition states and intermediate states in the thrombin, factor Xa, plasmin and activated protein C–catalyzed reactions revealed that specific binding of effectors at S(n), n = 1–4 and S’(n), n = 1–3 and at remote exosites eli...

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Detaylı Bibliyografya
Yayımlandı:Life (Basel)
Yazar: Kovach, Ildiko M
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: MDPI 2021
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC8146069/
https://ncbi.nlm.nih.gov/pubmed/33925363
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/life11050396
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