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THE NATURE OF GENERAL BASE-GENERAL ACID CATALYSIS IN SERINE PROTEASES

The high reactivity of the serine residue at the active site of serine proteases is often attributed to the formation of a hydrogen bond between this serine and a histidine residue. In the case of the serine protease subtilisin, the catalytic serine residue can be specifically replaced by a cysteine...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Polgár, L., Bender, Myron L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1969
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC223289/
https://ncbi.nlm.nih.gov/pubmed/5271756
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