Transduction of Pig Small Airway Epithelial Cells and Distal Lung Progenitor Cells by AAV4

Cystic fibrosis (CF) is caused by genetic mutations of the CF transmembrane conductance regulator (CFTR), leading to disrupted transport of Cl(−) and bicarbonate and CF lung disease featuring bacterial colonization and chronic infection in conducting airways. CF pigs engineered by mutating CFTR deve...

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Publicado no:Cells
Main Authors: Chen, Oliver G., Mather, Steven E., Brommel, Christian M., Hamilton, Bradley A., Ehler, Annie, Villacreses, Raul, Girgis, Reda E., Abou Alaiwa, Mahmoud, Stoltz, David A., Zabner, Joseph, Li, Xiaopeng
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8145967/
https://ncbi.nlm.nih.gov/pubmed/33923029
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells10051014
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