Transduction of Pig Small Airway Epithelial Cells and Distal Lung Progenitor Cells by AAV4

Cystic fibrosis (CF) is caused by genetic mutations of the CF transmembrane conductance regulator (CFTR), leading to disrupted transport of Cl(−) and bicarbonate and CF lung disease featuring bacterial colonization and chronic infection in conducting airways. CF pigs engineered by mutating CFTR deve...

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Vydáno v:Cells
Hlavní autoři: Chen, Oliver G., Mather, Steven E., Brommel, Christian M., Hamilton, Bradley A., Ehler, Annie, Villacreses, Raul, Girgis, Reda E., Abou Alaiwa, Mahmoud, Stoltz, David A., Zabner, Joseph, Li, Xiaopeng
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2021
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8145967/
https://ncbi.nlm.nih.gov/pubmed/33923029
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells10051014
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