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AAV-6 mediated efficient transduction of mouse lower airways

AAV1 and AAV6 are two closely related AAV serotypes. In the present study, we found AAV6 was more efficient in transducing mouse lower airway epithelia in vitro and in vivo than AAV1. To further explore the mechanism of this difference, we found that significantly more AAV1 bound to mouse airway epi...

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Detalhes bibliográficos
Main Authors: Li, Wuping, Zhang, Liqun, Wu, Zhijian, Pickles, Raymond J., Samulski, R. Jude
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3163804/
https://ncbi.nlm.nih.gov/pubmed/21752418
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2011.06.009
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