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Adeno-Associated Virus Type 6 (AAV6) Vectors Mediate Efficient Transduction of Airway Epithelial Cells in Mouse Lungs Compared to That of AAV2 Vectors

Although vectors derived from adeno-associated virus type 2 (AAV2) promote gene transfer and expression in many somatic tissues, studies with animal models and cultured cells show that the apical surface of airway epithelia is resistant to transduction by AAV2 vectors. Approaches to increase transdu...

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Библиографические подробности
Главные авторы: Halbert, Christine L., Allen, James M., Miller, A. Dusty
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology 2001
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC114385/
https://ncbi.nlm.nih.gov/pubmed/11413329
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.75.14.6615-6624.2001
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