Adeno-Associated Virus Type 6 (AAV6) Vectors Mediate Efficient Transduction of Airway Epithelial Cells in Mouse Lungs Compared to That of AAV2 Vectors

Although vectors derived from adeno-associated virus type 2 (AAV2) promote gene transfer and expression in many somatic tissues, studies with animal models and cultured cells show that the apical surface of airway epithelia is resistant to transduction by AAV2 vectors. Approaches to increase transdu...

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הוצא לאור ב:	J Virol
Principais autores:	Halbert, Christine L., Allen, James M., Miller, A. Dusty
פורמט:	Artigo
שפה:	Inglês
יצא לאור:	American Society for Microbiology (ASM) 2001
נושאים:	Gene Therapy
גישה מקוונת:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC114385/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11413329/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.75.14.6615-6624.2001
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