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S100P Interacts with p53 while Pentamidine Inhibits This Interaction
S100P, a small calcium-binding protein, associates with the p53 protein with micromolar affinity. It has been hypothesized that the oncogenic function of S100P may involve binding-induced inactivation of p53. We used (1)H-(15)N HSQC experiments and molecular modeling to study the molecular interacti...
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| Published in: | Biomolecules |
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| Main Authors: | , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
MDPI
2021
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8145327/ https://ncbi.nlm.nih.gov/pubmed/33923162 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom11050634 |
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