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Lysozyme as the anti-proliferative agent to block the interaction between S100A6 and the RAGE V domain

In this report, using NMR and molecular modeling, we have studied the structure of lysozyme-S100A6 complex and the influence of tranilast [N-(3, 4-dimethoxycinnamoyl) anthranilic acid], an antiallergic drug which binds to lysozyme, on lysozyme-S100A6 and S100A6-RAGE complex formation and, finally, o...

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Dettagli Bibliografici
Pubblicato in:PLoS One
Autori principali: Khan, Md. Imran, Dowarha, Deepu, Katte, Revansiddha, Chou, Ruey-Hwang, Filipek, Anna, Yu, Chin
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6508705/
https://ncbi.nlm.nih.gov/pubmed/31071146
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0216427
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