Integrated genomics and comprehensive validation reveal drivers of genomic evolution in esophageal adenocarcinoma

Esophageal adenocarcinoma (EAC) is associated with a marked genomic instability, which underlies disease progression and development of resistance to treatment. In this study, we used an integrated genomics approach to identify a genomic instability signature. Here we show that elevated expression o...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Commun Biol
Egile Nagusiak: Kumar, Subodh, Buon, Leutz, Talluri, Srikanth, Roncador, Marco, Liao, Chengcheng, Zhao, Jiangning, Shi, Jialan, Chakraborty, Chandraditya, Gonzalez, Gabriel, Tai, Yu-Tzu, Prabhala, Rao, Samur, Mehmet K., Munshi, Nikhil C., Shammas, Masood A.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group UK 2021
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC8144613/
https://ncbi.nlm.nih.gov/pubmed/34031527
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s42003-021-02125-x
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