Impact of RAD51C-mediated Homologous Recombination on Genomic Integrity in Barrett’s Adenocarcinoma Cells

BACKGROUND: In normal cells, RAD51-mediated homologous recombination (HR) is a precise DNA repair mechanism which plays a key role in the maintenance of genomic integrity and stability. However, elevated (dysregulated) RAD51 is implicated in genomic instability and is a potential target for treatmen...

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Detalhes bibliográficos
Publicado no:J Gastroenterol Hepatol Res
Principais autores: Pal, Jagannath, Nanjappa, Purushothama, Kumar, Subodh, Shi, Jialan, Buon, Leutz, Munshi, Nikhil C., Shammas, Masood A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5796564/
https://ncbi.nlm.nih.gov/pubmed/29399538
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.17554/j.issn.2224-3992.2017.06.687
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