RAD51 Inhibitor Reverses Etoposide-Induced Genomic Toxicity and Instability in Esophageal Adenocarcinoma Cells

AIM: In normal cells, homologous recombination (HR) is strictly regulated and precise and plays an important role in preserving genomic integrity by accurately repairing DNA damage. RAD51 is the recombinase which mediates homologous base pairing and strand exchange during DNA repair by HR. We have p...

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Bibliographic Details
Published in:Arch Clin Toxicol (Middlet)
Main Authors: Liao, Chengcheng, Zhao, Jiangning, Kumar, Subodh, Chakraborty, Chandraditya, Talluri, Srikanth, Munshi, Nikhil C., Shammas, Masood A.
Format: Artigo
Language:Inglês
Published: 2020
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7508453/
https://ncbi.nlm.nih.gov/pubmed/32968740
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.46439/toxicology.2.006
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