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Activation of IGF-1 pathway and suppression of atrophy related genes are involved in Epimedium extract (icariin) promoted C2C12 myotube hypertrophy

The regenerative effect of Epimedium and its major bioactive flavonoid icariin (ICA) have been documented in traditional medicine, but their effect on sarcopenia has not been evaluated. The aim of this study was to investigate the effects of Epimedium extract (EE) on skeletal muscle as represented b...

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Publicado en:Sci Rep
Autores principales: Lin, Yi-An, Li, Yan-Rong, Chang, Yi-Ching, Hsu, Mei-Chich, Chen, Szu-Tah
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group UK 2021
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC8144409/
https://ncbi.nlm.nih.gov/pubmed/34031457
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-89039-0
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