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Activation of IGF-1 pathway and suppression of atrophy related genes are involved in Epimedium extract (icariin) promoted C2C12 myotube hypertrophy

The regenerative effect of Epimedium and its major bioactive flavonoid icariin (ICA) have been documented in traditional medicine, but their effect on sarcopenia has not been evaluated. The aim of this study was to investigate the effects of Epimedium extract (EE) on skeletal muscle as represented b...

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Detalles Bibliográficos
Publicado en:Sci Rep
Main Authors: Lin, Yi-An, Li, Yan-Rong, Chang, Yi-Ching, Hsu, Mei-Chich, Chen, Szu-Tah
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group UK 2021
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC8144409/
https://ncbi.nlm.nih.gov/pubmed/34031457
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-89039-0
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