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Activation of IGF-1 pathway and suppression of atrophy related genes are involved in Epimedium extract (icariin) promoted C2C12 myotube hypertrophy

The regenerative effect of Epimedium and its major bioactive flavonoid icariin (ICA) have been documented in traditional medicine, but their effect on sarcopenia has not been evaluated. The aim of this study was to investigate the effects of Epimedium extract (EE) on skeletal muscle as represented b...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Lin, Yi-An, Li, Yan-Rong, Chang, Yi-Ching, Hsu, Mei-Chich, Chen, Szu-Tah
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8144409/
https://ncbi.nlm.nih.gov/pubmed/34031457
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-89039-0
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