TAZ-CAMTA1 and YAP-TFE3 alter the TAZ/YAP transcriptome by recruiting the ATAC histone acetyltransferase complex

Epithelioid hemangioendothelioma (EHE) is a vascular sarcoma that metastasizes early in its clinical course and lacks an effective medical therapy. The TAZ-CAMTA1 and YAP-TFE3 fusion proteins are chimeric transcription factors and initiating oncogenic drivers of EHE. A combined proteomic/genetic scr...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Merritt, Nicole, Garcia, Keith, Rajendran, Dushyandi, Lin, Zhen-Yuan, Zhang, Xiaomeng, Mitchell, Katrina A, Borcherding, Nicholas, Fullenkamp, Colleen, Chimenti, Michael S, Gingras, Anne-Claude, Harvey, Kieran F, Tanas, Munir R
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2021
Assuntos:
Cancer Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8143797/
https://ncbi.nlm.nih.gov/pubmed/33913810
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.62857
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