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Mechanism of action of a WWTR1(TAZ)-CAMTA1 fusion oncoprotein
The WWTR1 (protein is known as TAZ) -CAMTA1 (WC) fusion gene defines epithelioid hemangioendothelioma, a malignant vascular cancer. TAZ (transcriptional coactivator with PDZ binding motif) is a transcriptional coactivator and end effector of the Hippo tumor suppressor pathway. It is inhibited by pho...
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| Publicado no: | Oncogene |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4983459/ https://ncbi.nlm.nih.gov/pubmed/25961935 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2015.148 |
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