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Murine Models of Lysosomal Storage Diseases Exhibit Differences in Brain Protein Aggregation and Neuroinflammation

Genetic, epidemiological and experimental evidence implicate lysosomal dysfunction in Parkinson’s disease (PD) and related synucleinopathies. Investigate several mouse models of lysosomal storage diseases (LSDs) and evaluate pathologies reminiscent of synucleinopathies. We obtained brain tissue from...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Biomedicines
Prif Awduron: Clarke, Jennifer, Kayatekin, Can, Viel, Catherine, Shihabuddin, Lamya, Sardi, Sergio Pablo
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: MDPI 2021
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC8143154/
https://ncbi.nlm.nih.gov/pubmed/33919140
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biomedicines9050446
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