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Murine Models of Lysosomal Storage Diseases Exhibit Differences in Brain Protein Aggregation and Neuroinflammation

Genetic, epidemiological and experimental evidence implicate lysosomal dysfunction in Parkinson’s disease (PD) and related synucleinopathies. Investigate several mouse models of lysosomal storage diseases (LSDs) and evaluate pathologies reminiscent of synucleinopathies. We obtained brain tissue from...

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Detalhes bibliográficos
Publicado no:Biomedicines
Main Authors: Clarke, Jennifer, Kayatekin, Can, Viel, Catherine, Shihabuddin, Lamya, Sardi, Sergio Pablo
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8143154/
https://ncbi.nlm.nih.gov/pubmed/33919140
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biomedicines9050446
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