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Sequential dynein effectors regulate axonal autophagosome motility in a maturation-dependent pathway
Autophagy is a degradative pathway required to maintain homeostasis. Neuronal autophagosomes form constitutively at the axon terminal and mature via lysosomal fusion during dynein-mediated transport to the soma. How the dynein–autophagosome interaction is regulated is unknown. Here, we identify mult...
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| 發表在: | J Cell Biol |
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| Main Authors: | , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Rockefeller University Press
2021
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8142281/ https://ncbi.nlm.nih.gov/pubmed/34014261 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.202010179 |
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