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Integrating Clinical and Polygenic Factors to Predict Breast Cancer Risk in Women Undergoing Genetic Testing

PURPOSE: Screening and prevention decisions for women at increased risk of developing breast cancer depend on genetic and clinical factors to estimate risk and select appropriate interventions. Integration of polygenic risk into clinical breast cancer risk estimators can improve discrimination. Howe...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:JCO Precis Oncol
Prif Awduron: Hughes, Elisha, Tshiaba, Placede, Wagner, Susanne, Judkins, Thaddeus, Rosenthal, Eric, Roa, Benjamin, Gallagher, Shannon, Meek, Stephanie, Dalton, Kathryn, Hedegard, Wade, Adami, Carol A., Grear, Danna F., Domchek, Susan M., Garber, Judy, Lancaster, Johnathan M., Weitzel, Jeffrey N., Kurian, Allison W., Lanchbury, Jerry S., Gutin, Alexander, Robson, Mark E.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society of Clinical Oncology 2021
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC8140787/
https://ncbi.nlm.nih.gov/pubmed/34036224
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/PO.20.00246
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