Germline pathogenic variants in the Ataxia Telangiectasia Mutated (ATM) gene are associated with high and moderate risks for multiple cancers

Pathogenic variants (PVs) in ATM are relatively common, but the scope and magnitude of risk remains uncertain. This study aimed to estimate ATM PV cancer risks independent of family cancer history. This analysis included patients referred for hereditary cancer testing with a multi-gene panel (N=627,...

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Bibliographic Details
Published in:Cancer Prev Res (Phila)
Main Authors: Hall, Michael J, Bernhisel, Ryan, Hughes, Elisha, Larson, Katie, Rosenthal, Eric T., Singh, Nanda A., Lancaster, Johnathan M., Kurian, Allison W
Format: Artigo
Language:Inglês
Published: 2021
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC8026745/
https://ncbi.nlm.nih.gov/pubmed/33509806
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1940-6207.CAPR-20-0448
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