Enhanced dengue vaccine virus replication and neutralizing antibody responses in immune primed rhesus macaques

Antibody-dependent enhancement (ADE) is suspected to influence dengue virus (DENV) infection, but the role ADE plays in vaccination strategies incorporating live attenuated virus components is less clear. Using a heterologous prime-boost strategy in rhesus macaques, we examine the effect of priming...

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Dades bibliogràfiques
Publicat a:NPJ Vaccines
Autors principals: McCracken, Michael K., Kuklis, Caitlin H., Kannadka, Chandrika B., Barvir, David A., Sanborn, Mark A., Waickman, Adam T., Siegfried, Hayden C., Victor, Kaitlin A., Hatch, Kristin L., De La Barrera, Rafael, Walls, Shannon D., Rutvisuttinunt, Wiriya, Currier, Jeffrey R., Friberg, Heather, Jarman, Richard G., Gromowski, Gregory D.
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2021
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8140083/
https://ncbi.nlm.nih.gov/pubmed/34021159
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41541-021-00339-y
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