Dissecting the heterogeneity of DENV vaccine-elicited cellular immunity using single-cell RNA sequencing and metabolic profiling

Generating effective and durable T cell immunity is a critical prerequisite for vaccination against dengue virus (DENV) and other viral diseases. However, understanding the molecular mechanisms of vaccine-elicited T cell immunity remains a critical knowledge gap in vaccinology. In this study, we uti...

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Publicado no:Nat Commun
Main Authors: Waickman, Adam T., Victor, Kaitlin, Li, Tao, Hatch, Kristin, Rutvisuttinunt, Wiriya, Medin, Carey, Gabriel, Benjamin, Jarman, Richard G., Friberg, Heather, Currier, Jeffrey R.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6694189/
https://ncbi.nlm.nih.gov/pubmed/31413301
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-11634-7
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