Transcriptional and clonal characterization of B cell plasmablast diversity following primary and secondary natural DENV infection

Antibody-mediated humoral immunity is thought to play a central role in mediating the immunopathogenesis of acute DENV infection, but limited data are available on the diversity, specificity, and functionality of the antibody response at the molecular level elicited by primary or secondary DENV infe...

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Veröffentlicht in:EBioMedicine
Hauptverfasser: Waickman, Adam T., Gromowski, Gregory D., Rutvisuttinunt, Wiriya, Li, Tao, Siegfried, Hayden, Victor, Kaitlin, Kuklis, Caitlin, Gomootsukavadee, Methee, McCracken, Michael K., Gabriel, Benjamin, Mathew, Anuja, Grinyo i Escuer, Ariadna, Fouch, Mallorie E., Liang, Jenny, Fernandez, Stefan, Davidson, Edgar, Doranz, Benjamin J., Srikiatkhachorn, Anon, Endy, Timothy, Thomas, Stephen J., Ellison, Damon, Rothman, Alan L., Jarman, Richard G., Currier, Jeffrey R., Friberg, Heather
Format: Artigo
Sprache:Inglês
Veröffentlicht: Elsevier 2020
Schlagworte:
Research paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7170960/
https://ncbi.nlm.nih.gov/pubmed/32315970
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2020.102733
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