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Glucose and NAADP trigger elementary intracellular β-cell Ca(2+) signals

Pancreatic β-cells release insulin upon a rise in blood glucose. The precise mechanisms of stimulus-secretion coupling, and its failure in Diabetes Mellitus Type 2, remain to be elucidated. The consensus model, as well as a class of currently prescribed anti-diabetic drugs, are based around the obse...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Heister, Paula Maria, Powell, Trevor, Galione, Antony
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8140081/
https://ncbi.nlm.nih.gov/pubmed/34021189
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-88906-0
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