Synthesis of the Ca(2+)-mobilizing messengers NAADP and cADPR by intracellular CD38 enzyme in the mouse heart: Role in β-adrenoceptor signaling

Nicotinic acid adenine dinucleotide phosphate (NAADP) and cyclic ADP-ribose (cADPR) are Ca(2+)-mobilizing messengers important for modulating cardiac excitation–contraction coupling and pathophysiology. CD38, which belongs to the ADP-ribosyl cyclase family, catalyzes synthesis of both NAADP and cADP...

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Detalles Bibliográficos
Publicado en:J Biol Chem
Main Authors: Lin, Wee K., Bolton, Emma L., Cortopassi, Wilian A., Wang, Yanwen, O'Brien, Fiona, Maciejewska, Matylda, Jacobson, Matthew P., Garnham, Clive, Ruas, Margarida, Parrington, John, Lei, Ming, Sitsapesan, Rebecca, Galione, Antony, Terrar, Derek A.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2017
Assuntos:
Cell Biology
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5555186/
https://ncbi.nlm.nih.gov/pubmed/28539361
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.789347
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