Synthesis of the Ca(2+)-mobilizing messengers NAADP and cADPR by intracellular CD38 enzyme in the mouse heart: Role in β-adrenoceptor signaling

Nicotinic acid adenine dinucleotide phosphate (NAADP) and cyclic ADP-ribose (cADPR) are Ca(2+)-mobilizing messengers important for modulating cardiac excitation–contraction coupling and pathophysiology. CD38, which belongs to the ADP-ribosyl cyclase family, catalyzes synthesis of both NAADP and cADP...

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Библиографические подробности
Опубликовано в: :J Biol Chem
Главные авторы: Lin, Wee K., Bolton, Emma L., Cortopassi, Wilian A., Wang, Yanwen, O'Brien, Fiona, Maciejewska, Matylda, Jacobson, Matthew P., Garnham, Clive, Ruas, Margarida, Parrington, John, Lei, Ming, Sitsapesan, Rebecca, Galione, Antony, Terrar, Derek A.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Biochemistry and Molecular Biology 2017
Предметы:
Cell Biology
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5555186/
https://ncbi.nlm.nih.gov/pubmed/28539361
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.789347
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