TPCs: Endolysosomal channels for Ca(2+) mobilization from acidic organelles triggered by NAADP

Two-pore channels (TPCs or TPCNs) are novel members of the large superfamily of voltage-gated cation channels with slightly higher sequence homology to the pore-forming subunits of voltage-gated Ca(2+) and Na(+) channels than most other members. Recent studies demonstrate that TPCs locate to endosom...

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Bibliographic Details
Main Authors: Zhu, Michael X., Ma, Jianjie, Parrington, John, Galione, Antony, Evans, A. Mark
Format: Artigo
Language:Inglês
Published: 2010
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2867333/
https://ncbi.nlm.nih.gov/pubmed/20159015
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.febslet.2010.02.028
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