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The luminal Ca(2+) chelator, TPEN, inhibits NAADP-induced Ca(2+) release

The regulation of Ca(2+) release by luminal Ca(2+) has been well studied for the ryanodine and IP(3) receptors but has been less clear for the NAADP-regulated channel. In view of conflicting reports, we have re-examined the issue by manipulating luminal Ca(2+) with the membrane-permeant, low affinit...

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Autors principals: Morgan, Anthony J., Parrington, John, Galione, Antony
Format: Artigo
Idioma:Inglês
Publicat: Elsevier 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3526783/
https://ncbi.nlm.nih.gov/pubmed/23099186
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ceca.2012.09.001
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