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The Acid Test: The Discovery of Two Pore Channels (TPCs) as NAADP-Gated Endolysosomal Ca(2+) Release Channels
In this review we describe the background and implications of our recent discovery that Two pore channels (TPCs) comprise a novel class of calcium release channels gated by the intracellular messenger nicotinic acid adenine dinucleotide phosphate (NAADP). Their localization to the endolysosomal syst...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2799329/ https://ncbi.nlm.nih.gov/pubmed/19475418 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00424-009-0682-y |
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