Physiologically-Based Pharmacokinetic Modeling Characterizes the CYP3A-Mediated Drug-Drug Interaction Between Fluconazole and Sildenafil in Infants

Physiologically-based pharmacokinetic (PBPK) modeling can potentially predict pediatric drug-drug interactions (DDIs) when clinical DDI data are limited. In infants for whom treatment of pulmonary hypertension and prevention or treatment of invasive candidiasis are indicated, sildenafil with flucona...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Clin Pharmacol Ther
Main Authors: Salerno, Sara N., Edginton, Andrea, Gerhart, Jacqueline G., Laughon, Matthew M., Ambalavanan, Namasivayam, Sokol, Gregory M., Hornik, Chi D., Stewart, Dan, Mills, Mary, Martz, Karen, Gonzalez, Daniel
Format: Artigo
Sprog:Inglês
Udgivet: 2020
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8138939/
https://ncbi.nlm.nih.gov/pubmed/32691891
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cpt.1990
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker