Integrated Isogenic Human Induced Pluripotent Stem Cell–Based Liver and Heart Microphysiological Systems Predict Unsafe Drug–Drug Interaction

Three-dimensional (3D) microphysiological systems (MPSs) mimicking human organ function in vitro are an emerging alternative to conventional monolayer cell culture and animal models for drug development. Human induced pluripotent stem cells (hiPSCs) have the potential to capture the diversity of hum...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Front Pharmacol
Egile Nagusiak: Lee-Montiel, Felipe T., Laemmle, Alexander, Charwat, Verena, Dumont, Laure, Lee, Caleb S., Huebsch, Nathaniel, Okochi, Hideaki, Hancock, Matthew J., Siemons, Brian, Boggess, Steven C., Goswami, Ishan, Miller, Evan W., Willenbring, Holger, Healy, Kevin E.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Frontiers Media S.A. 2021
Gaiak:
Pharmacology
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC8138446/
https://ncbi.nlm.nih.gov/pubmed/34025426
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2021.667010
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