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Improved Computational Identification of Drug Response Using Optical Measurements of Human Stem Cell Derived Cardiomyocytes in Microphysiological Systems

Cardiomyocytes derived from human induced pluripotent stem cells (hiPSC-CMs) hold great potential for drug screening applications. However, their usefulness is limited by the relative immaturity of the cells’ electrophysiological properties as compared to native cardiomyocytes in the adult human hea...

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Detalhes bibliográficos
Publicado no:Front Pharmacol
Main Authors: Jæger, Karoline Horgmo, Charwat, Verena, Charrez, Bérénice, Finsberg, Henrik, Maleckar, Mary M., Wall, Samuel, Healy, Kevin E., Tveito, Aslak
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7029356/
https://ncbi.nlm.nih.gov/pubmed/32116671
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2019.01648
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