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Improved Computational Identification of Drug Response Using Optical Measurements of Human Stem Cell Derived Cardiomyocytes in Microphysiological Systems

Cardiomyocytes derived from human induced pluripotent stem cells (hiPSC-CMs) hold great potential for drug screening applications. However, their usefulness is limited by the relative immaturity of the cells’ electrophysiological properties as compared to native cardiomyocytes in the adult human hea...

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發表在:Front Pharmacol
Main Authors: Jæger, Karoline Horgmo, Charwat, Verena, Charrez, Bérénice, Finsberg, Henrik, Maleckar, Mary M., Wall, Samuel, Healy, Kevin E., Tveito, Aslak
格式: Artigo
語言:Inglês
出版: Frontiers Media S.A. 2020
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7029356/
https://ncbi.nlm.nih.gov/pubmed/32116671
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2019.01648
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