Inversion and computational maturation of drug response using human stem cell derived cardiomyocytes in microphysiological systems

While cardiomyocytes differentiated from human induced pluripotent stems cells (hiPSCs) hold great promise for drug screening, the electrophysiological properties of these cells can be variable and immature, producing results that are significantly different from their human adult counterparts. Here...

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Vydáno v:Sci Rep
Hlavní autoři: Tveito, Aslak, Jæger, Karoline Horgmo, Huebsch, Nathaniel, Charrez, Bérénice, Edwards, Andrew G., Wall, Samuel, Healy, Kevin E.
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2018
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6279833/
https://ncbi.nlm.nih.gov/pubmed/30514966
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-35858-7
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