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Inversion and computational maturation of drug response using human stem cell derived cardiomyocytes in microphysiological systems

While cardiomyocytes differentiated from human induced pluripotent stems cells (hiPSCs) hold great promise for drug screening, the electrophysiological properties of these cells can be variable and immature, producing results that are significantly different from their human adult counterparts. Here...

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Bibliografiske detaljer
Udgivet i:Sci Rep
Main Authors: Tveito, Aslak, Jæger, Karoline Horgmo, Huebsch, Nathaniel, Charrez, Bérénice, Edwards, Andrew G., Wall, Samuel, Healy, Kevin E.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6279833/
https://ncbi.nlm.nih.gov/pubmed/30514966
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-35858-7
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