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Inversion and computational maturation of drug response using human stem cell derived cardiomyocytes in microphysiological systems

While cardiomyocytes differentiated from human induced pluripotent stems cells (hiPSCs) hold great promise for drug screening, the electrophysiological properties of these cells can be variable and immature, producing results that are significantly different from their human adult counterparts. Here...

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書目詳細資料
發表在:Sci Rep
Main Authors: Tveito, Aslak, Jæger, Karoline Horgmo, Huebsch, Nathaniel, Charrez, Bérénice, Edwards, Andrew G., Wall, Samuel, Healy, Kevin E.
格式: Artigo
語言:Inglês
出版: Nature Publishing Group UK 2018
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6279833/
https://ncbi.nlm.nih.gov/pubmed/30514966
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-35858-7
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