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Inversion and computational maturation of drug response using human stem cell derived cardiomyocytes in microphysiological systems

While cardiomyocytes differentiated from human induced pluripotent stems cells (hiPSCs) hold great promise for drug screening, the electrophysiological properties of these cells can be variable and immature, producing results that are significantly different from their human adult counterparts. Here...

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Publicado en:Sci Rep
Autores principales: Tveito, Aslak, Jæger, Karoline Horgmo, Huebsch, Nathaniel, Charrez, Bérénice, Edwards, Andrew G., Wall, Samuel, Healy, Kevin E.
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group UK 2018
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6279833/
https://ncbi.nlm.nih.gov/pubmed/30514966
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-35858-7
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