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Human induced pluripotent stem cell-based microphysiological tissue models of myocardium and liver for drug development

Drug discovery and development to date has relied on animal models, which are useful but are often expensive, slow, and fail to mimic human physiology. The discovery of human induced pluripotent stem (iPS) cells has led to the emergence of a new paradigm of drug screening using human and disease-spe...

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Detalhes bibliográficos
Main Authors: Mathur, Anurag, Loskill, Peter, Hong, SoonGweon, Lee, Jae Young, Marcus, Sivan G, Dumont, Laure, Conklin, Bruce R, Willenbring, Holger, Lee, Luke P, Healy, Kevin E
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4029618/
https://ncbi.nlm.nih.gov/pubmed/24565415
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/scrt375
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