PROTAC: An Effective Targeted Protein Degradation Strategy for Cancer Therapy

Proteolysis targeting chimeric (PROTAC) technology is an effective endogenous protein degradation tool developed in recent years that can ubiquitinate the target proteins through the ubiquitin-proteasome system (UPS) to achieve an effect on tumor growth. A number of literature studies on PROTAC tech...

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Bibliografiska uppgifter
I publikationen:Front Pharmacol
Huvudupphovsmän: Qi, Si-Min, Dong, Jinyun, Xu, Zhi-Yuan, Cheng, Xiang-Dong, Zhang, Wei-Dong, Qin, Jiang-Jiang
Materialtyp: Artigo
Språk:Inglês
Publicerad: Frontiers Media S.A. 2021
Ämnen:
Pharmacology
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC8138175/
https://ncbi.nlm.nih.gov/pubmed/34025443
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2021.692574
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