PROTAC: An Effective Targeted Protein Degradation Strategy for Cancer Therapy

Proteolysis targeting chimeric (PROTAC) technology is an effective endogenous protein degradation tool developed in recent years that can ubiquitinate the target proteins through the ubiquitin-proteasome system (UPS) to achieve an effect on tumor growth. A number of literature studies on PROTAC tech...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Front Pharmacol
Main Authors: Qi, Si-Min, Dong, Jinyun, Xu, Zhi-Yuan, Cheng, Xiang-Dong, Zhang, Wei-Dong, Qin, Jiang-Jiang
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2021
Teme:
Pharmacology
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC8138175/
https://ncbi.nlm.nih.gov/pubmed/34025443
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2021.692574
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