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Targeting MDMX for Cancer Therapy: Rationale, Strategies, and Challenges
The oncogene MDMX, also known as MDM4 is a critical negative regulator of the tumor suppressor p53 and has been implicated in the initiation and progression of human cancers. Increasing evidence indicates that MDMX is often amplified and highly expressed in human cancers, promotes cancer cell growth...
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| Publicado no: | Front Oncol |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Frontiers Media S.A.
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7419686/ https://ncbi.nlm.nih.gov/pubmed/32850448 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2020.01389 |
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